miR-204-5p suppresses hepatocellular cancer proliferation by regulating homeoprotein SIX1 expression
نویسندگان
چکیده
منابع مشابه
miR‐204‐5p suppresses hepatocellular cancer proliferation by regulating homeoprotein SIX1 expression
Fewer than 30% of patients with hepatocellular carcinoma (HCC) are eligible to receive curative therapies, and so a better understanding of the molecular mechanisms of HCC is needed to identify potential therapeutic targets. The role of microRNA (miRNA) in modulating tumour progression has been demonstrated, and therapies targeting miRNA appear promising. miR-204-5p has been shown to function i...
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Background: Clear cell renal cell carcinoma (ccRCC) represents approximately 70% of RCC,as the most frequent histological subtype of RCC. MiR-138-5p, a tumor-related microRNA (miRNA), has been reported to be implicated in the diverse types of human malignancies, but its role in ccRCCremains unclear. Objective: The study was designed to investigate the function...
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Decreased level of miR-204-5p has been documented in various malignancies. However, the expression and clinical significance of miR-204-5p in hepatocellular carcinoma has not been investigated. The aim of this study is to examine the relationship between miR-204-5p expression and clinicopathological features in hepatocellular carcinoma (HCC) as well as to predict the relevant signaling pathways...
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ژورنال
عنوان ژورنال: FEBS Open Bio
سال: 2018
ISSN: 2211-5463
DOI: 10.1002/2211-5463.12363